sigma plot 12 scientific graphing software (SPSS Inc)
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sigma plot 12 scientific graphing software
Sigma Plot 12 Scientific Graphing Software, supplied by SPSS Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sigma+plot+12+scientific+graphing+software/sigma+plot+12+5/pm29320899-61-31-36
Average 90 stars, based on 1 article reviews
Sigma Plot 12 Scientific Graphing Software, supplied by SPSS Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sigma+plot+12+scientific+graphing+software/sigma+plot+12+5/pm29320899-61-31-36
Average 90 stars, based on 1 article reviews
sigma plot 12 scientific graphing software - by Bioz Stars,
2026-10
90/100 stars
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Concentration Assay:Article Title: Influence of Amlodipine Enantiomers on Human Microsomal Cytochromes P450: Stereoselective Time-Dependent Inhibition of CYP3A Enzyme Activity Article Snippet: Inhibition of individual CYP activities was evaluated by plotting the remaining activity against the inhibitor concentration using GraphPad Prism (La Jolla, CA, USA). .. IC 50 values were obtained by analyzing plots of the logarithm of the inhibitor concentration against the percentage of activity remaining after inhibition using the Sigma Article Title: Optical isomers of dihydropyridine calcium channel blockers display enantiospecific effects on the expression and enzyme activities of human xenobiotics-metabolizing cytochromes P450. Article Snippet: Dihydropyridine calcium channel blockers (CCBs) are used as anti-hypertensives and in the treatment of angina pectoris.. Structurally, CCBs have at least one chiral center in the molecule, thereby existing in two or more different enantiomers.. In the current paper we examined effects of benidipine, felodipine and isradipine enantiomers on the expression and enzyme activities of human xenobiotics-metabolizing Article Title: In vitro analysis of itraconazole cis-diastereoisomers inhibition of nine cytochrome P450 enzymes: stereoselective inhibition of CYP3A. Article Snippet: Itraconazole (ITZ), an antifungal azole derivate is a chiral drug that consists of four cisdiastereoisomers ((+)-2R,4S,2′R-ITZ-A; (+)-2R,4S,2′S-ITZ-B; (−)2S,4R,2′S-ITZ-C and (−) 2S,4R,2′R-ITZ-D) which may differ in their pharmacokinetics and pharmacodynamics.. As itraconazole is known as a CYP3A4 inhibitor causing severe drug-drug interaction, the inhibitory potencies of its individual optical isomers towards nine drug-metabolising cytochrome P450 (including CYP3A, CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6 and CYP2E1), were investigated.. All itraconazole diastereoisomers dose-dependently inhibited CYP3A activity in both used assays, midazolam and testosterone hydroxylation. Activity Assay:Article Title: Influence of Amlodipine Enantiomers on Human Microsomal Cytochromes P450: Stereoselective Time-Dependent Inhibition of CYP3A Enzyme Activity Article Snippet: Inhibition of individual CYP activities was evaluated by plotting the remaining activity against the inhibitor concentration using GraphPad Prism (La Jolla, CA, USA). .. IC 50 values were obtained by analyzing plots of the logarithm of the inhibitor concentration against the percentage of activity remaining after inhibition using the Sigma Article Title: Optical isomers of dihydropyridine calcium channel blockers display enantiospecific effects on the expression and enzyme activities of human xenobiotics-metabolizing cytochromes P450. Article Snippet: Dihydropyridine calcium channel blockers (CCBs) are used as anti-hypertensives and in the treatment of angina pectoris.. Structurally, CCBs have at least one chiral center in the molecule, thereby existing in two or more different enantiomers.. In the current paper we examined effects of benidipine, felodipine and isradipine enantiomers on the expression and enzyme activities of human xenobiotics-metabolizing Article Title: In vitro analysis of itraconazole cis-diastereoisomers inhibition of nine cytochrome P450 enzymes: stereoselective inhibition of CYP3A. Article Snippet: Itraconazole (ITZ), an antifungal azole derivate is a chiral drug that consists of four cisdiastereoisomers ((+)-2R,4S,2′R-ITZ-A; (+)-2R,4S,2′S-ITZ-B; (−)2S,4R,2′S-ITZ-C and (−) 2S,4R,2′R-ITZ-D) which may differ in their pharmacokinetics and pharmacodynamics.. As itraconazole is known as a CYP3A4 inhibitor causing severe drug-drug interaction, the inhibitory potencies of its individual optical isomers towards nine drug-metabolising cytochrome P450 (including CYP3A, CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6 and CYP2E1), were investigated.. All itraconazole diastereoisomers dose-dependently inhibited CYP3A activity in both used assays, midazolam and testosterone hydroxylation. Inhibition:Article Title: Influence of Amlodipine Enantiomers on Human Microsomal Cytochromes P450: Stereoselective Time-Dependent Inhibition of CYP3A Enzyme Activity Article Snippet: Inhibition of individual CYP activities was evaluated by plotting the remaining activity against the inhibitor concentration using GraphPad Prism (La Jolla, CA, USA). .. IC 50 values were obtained by analyzing plots of the logarithm of the inhibitor concentration against the percentage of activity remaining after inhibition using the Sigma Article Title: Optical isomers of dihydropyridine calcium channel blockers display enantiospecific effects on the expression and enzyme activities of human xenobiotics-metabolizing cytochromes P450. Article Snippet: Dihydropyridine calcium channel blockers (CCBs) are used as anti-hypertensives and in the treatment of angina pectoris.. Structurally, CCBs have at least one chiral center in the molecule, thereby existing in two or more different enantiomers.. In the current paper we examined effects of benidipine, felodipine and isradipine enantiomers on the expression and enzyme activities of human xenobiotics-metabolizing Article Title: In vitro analysis of itraconazole cis-diastereoisomers inhibition of nine cytochrome P450 enzymes: stereoselective inhibition of CYP3A. Article Snippet: Itraconazole (ITZ), an antifungal azole derivate is a chiral drug that consists of four cisdiastereoisomers ((+)-2R,4S,2′R-ITZ-A; (+)-2R,4S,2′S-ITZ-B; (−)2S,4R,2′S-ITZ-C and (−) 2S,4R,2′R-ITZ-D) which may differ in their pharmacokinetics and pharmacodynamics.. As itraconazole is known as a CYP3A4 inhibitor causing severe drug-drug interaction, the inhibitory potencies of its individual optical isomers towards nine drug-metabolising cytochrome P450 (including CYP3A, CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6 and CYP2E1), were investigated.. All itraconazole diastereoisomers dose-dependently inhibited CYP3A activity in both used assays, midazolam and testosterone hydroxylation. Software:Article Title: Influence of Amlodipine Enantiomers on Human Microsomal Cytochromes P450: Stereoselective Time-Dependent Inhibition of CYP3A Enzyme Activity Article Snippet: Inhibition of individual CYP activities was evaluated by plotting the remaining activity against the inhibitor concentration using GraphPad Prism (La Jolla, CA, USA). .. IC 50 values were obtained by analyzing plots of the logarithm of the inhibitor concentration against the percentage of activity remaining after inhibition using the Sigma Article Title: Optical isomers of dihydropyridine calcium channel blockers display enantiospecific effects on the expression and enzyme activities of human xenobiotics-metabolizing cytochromes P450. Article Snippet: Dihydropyridine calcium channel blockers (CCBs) are used as anti-hypertensives and in the treatment of angina pectoris.. Structurally, CCBs have at least one chiral center in the molecule, thereby existing in two or more different enantiomers.. In the current paper we examined effects of benidipine, felodipine and isradipine enantiomers on the expression and enzyme activities of human xenobiotics-metabolizing Article Title: In vitro analysis of itraconazole cis-diastereoisomers inhibition of nine cytochrome P450 enzymes: stereoselective inhibition of CYP3A. Article Snippet: Itraconazole (ITZ), an antifungal azole derivate is a chiral drug that consists of four cisdiastereoisomers ((+)-2R,4S,2′R-ITZ-A; (+)-2R,4S,2′S-ITZ-B; (−)2S,4R,2′S-ITZ-C and (−) 2S,4R,2′R-ITZ-D) which may differ in their pharmacokinetics and pharmacodynamics.. As itraconazole is known as a CYP3A4 inhibitor causing severe drug-drug interaction, the inhibitory potencies of its individual optical isomers towards nine drug-metabolising cytochrome P450 (including CYP3A, CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6 and CYP2E1), were investigated.. All itraconazole diastereoisomers dose-dependently inhibited CYP3A activity in both used assays, midazolam and testosterone hydroxylation. |